For your research needs, we offer metabolite profiling and absolute quantification of your metabolites by UHPLC-MS.
Due to the complexity of metabolomics experiments, we would like to meet you for discussing the details of your project. Once a strategy has been established, sample analysis will be scheduled. Please fill out and submit the Project information form. For further information or to schedule a meeting, please contact us.
The table below summarizes the LC-MS based analysis available in our facility. In addition, the Center of Laboratory Medicine offers over 350 routine analysis Prices are available on request.
|Acylcarnitine profile (28)||Plasma, serum, dried blood spot||Quantitative||Available|
|Amino acids profile (35)||Plasma||Quantitative||Available|
|Lipid profile (LPS, PI, PC, PE, Cer, SM, CE, DG, TG, list available on request)||Plasma, serum||Semi-quantitative||Available|
|Energy metabolism||Cells||Quantitative||Coming soon|
|Targeted metabolic profile (110)||Plasma, serum||Relative||Available|
|Non-targeted metabolic profile||Plasma, serum, tissue, urine, cells||Relative||On request|
|Uracil, dihydrouracil, β-ureidopropionic acid, β-alanine||Plasma||Quantitative||Available|
|Folate metabolism (6)||Plasma||Quantitative||Available|
|Bile acids profile (16)||Plasma, serum||Relative||Available|
|Therapeutic drugs & metabolites||Matrix||Type*||Status|
|Rivaroxaban, Apixaban, Edoxaban, Edoxaban M4||Plasma||Quantitative||Available|
|Capecitabine , 5’-DFCR, 5’-DFUR, Uridine||Plasma||Quantitative||Available|
|5-Fluorouracil, 5-fluorodihydrouracil, fluoro-β-ureidopropionic acid, fluoro-β-alanine||Plasma||Quantitative||Available|
|Sirolimus, Tacrolimus, Everolimus, Cyclosporin||Plasma, tissue||Quantitative||Available|
|Antifungal (7)||Plasma, serum||Quantitative||Available|
|Insulin & analogs||Plasma||Quantitative||Available|
|7α-hydroxy-4-cholesten-3-one (bile acid precursor)||Serum||Quantitative||Available|
- Relative: fold change information are given by comparing the peak area of metabolites, no calibration curve is used
- Semi-quantitative: concentration values are given based on a calibration curve obtained with a metabolite standard having similar physicochemical properties
- Quantitative: concentration values are given based on a calibration curve obtained with authentic chemical standard of the metabolites. The method uses isotopically labeled metabolites and is usually validated