For your research needs, we offer metabolite profiling and absolute quantification of your metabolites by UHPLC-MS.
Due to the complexity of metabolomics experiments, we would like to meet you for discussing the details of your project. Once a strategy has been established, sample analysis will be scheduled. Please fill out and submit the Project information form. For further information or to schedule a meeting, please contact us.
The table below summarizes the LC-MS based analysis available in our facility. In addition, the Center of Laboratory Medicine offers over 350 routine analysis for quantifying metabolites in your samples (e.g., amino acid profile, organic acids profile). Prices are available on request.
|Non-targeted metabolic profile (C18 and HILIC)||Plasma, serum, tissue, urine, cells||Relative||Available|
|Lipid profile (list available on request, e.g., LPS, PI, PC, PE, Cer, SM, CE, DG, TG)||Plasma, serum||Semi-quantitative||Available|
|Targeted metabolic profile (110)||Plasma, serum||Relative||Available|
|Acylcarnitine profile (28)||Plasma, serum, dried blood spot||Quantitative||Available|
|Steroid profile (17)||Plasma, serum||Quantitative||Available|
|Bile acids profile (16)||Plasma, serum||Relative||Available|
|Amino acids profile||Plasma||Quantitative||Available|
|Uracil and metabolites (dihydrouracil, β-ureidopropionic acid, β-alanine)||Plasma||Quantitative||Available|
|Folic acid and metabolites||Plasma||Quantitative||Coming soon|
|Therapeutic drugs & metabolites||Matrix||Type*||Status|
|Sirolimus, Tacrolimus, Everolimus, Cyclosporin||Plasma, tissue||Quantitative||Available|
|Capecitabine and metabolites||Plasma||Quantitative||Available|
|Antifungal (7)||Plasma, serum||Quantitative||Available|
|5-Fluorouracil and metabolites (5-fluorodihydrouracil, fluoro-β-ureidopropionic acid, fluoro-β-alanine)||Plasma||Quantitative||Available|
|Rivaroxaban, Apixaban, Edoxaban, Edoxaban M4||Plasma||Quantitative||Available|
|Insulin & analogs||Plasma||Quantitative||Available|
|7α-hydroxy-4-cholesten-3-one (bile acid precursor)||Serum||Quantitative||Available|
|Albumin profile||Plasma, serum||Relative||Available|
- Relative: fold change information are given by comparing the peak area of metabolites, no calibration curve is used
- Semi-quantitative: concentration values are given based on a calibration curve obtained with a metabolite standard having similar physicochemical properties
- Quantitative: concentration values are given based on a calibration curve obtained with authentic chemical standard of the metabolites. The method uses isotopically labeled metabolites and is usually validated